Best Sleep Aid Supplement of 2025

By Joshua Shafley
April 2025
Can’t sleep? Join the club.
With 1 in 3 Americans not getting enough sleep, the supplement industry is working overtime to help you catch those Zs.
I’ve dug through the research on this year’s top sleep supplements so you don’t have to lie awake wondering.

Jacked Factory Lean PM Night Time Fat Burner
This wins the Best for Multifunctional Nighttime Support award. Perfect if you want your sleep supplement pulling double duty on your waistline.

Magnesium Glycinate 400mg | High Absorption Formula
This earns the Best for Muscle Relaxation and Calm Sleep award. It’s the Toyota Camry of sleep aids – reliable, effective, no surprises.

DR. EMIL NUTRITION 5-HTP Plus with SAM-e
This gets the Best for Mood and Stress-Related Sleep Support award. If your brain won’t shut up at night, this might be your answer.

Nested Naturals Luna Kids Sleep Gummies
This wins the Best for Children’s Sleep Support award. It’s the peace treaty in the bedtime battle.
Jacked Factory Lean PM Night Time Fat Burner

This wins the Best for Multifunctional Nighttime Support award. Perfect if you want your sleep supplement pulling double duty on your waistline.
This is the Swiss Army knife of sleep aids.
It’s not just trying to knock you out – it’s also suppressing your appetite and burning fat while you sleep. Ambitious, right?
The good stuff:
- No stimulants (thank god, or you’d never sleep)
- 120 veggie capsules (2-4 month supply)
- Works for weight management and sleep in one pill
The not-so-good:
- Jack of all trades, master of none? If you just want sleep, there’s a lot of extra stuff in here
- Mixed reviews on how well it works for sleep specifically
- If you’re sensitive to appetite suppressants, proceed with caution
Magnesium Glycinate 400mg | High Absorption Formula

This earns the Best for Muscle Relaxation and Calm Sleep award. It’s the Toyota Camry of sleep aids – reliable, effective, no surprises.
Ah, magnesium. The mineral that half of us don’t get enough of.
This isn’t your grandma’s magnesium that gives you bathroom emergencies. It’s magnesium glycinate – the gentle, highly absorbable form that actually works.
The good stuff:
- 400mg is the sweet spot for sleep benefits
- Helps with muscle relaxation (bye-bye, leg cramps)
- Bonus benefits for heart, bones, and nerves
The not-so-good:
- 400mg might be overkill if you’re already getting enough from diet
- Not a knockout pill – it’s subtle
- Skip this if you have kidney issues
DR. EMIL NUTRITION 5-HTP Plus with SAM-e

This gets the Best for Mood and Stress-Related Sleep Support award. If your brain won’t shut up at night, this might be your answer.
This one’s for the overthinkers and the stressed-out.
5-HTP is the precursor to serotonin (your happy hormone), and SAM-e helps with mood. Together, they’re trying to help you stop spiraling about tomorrow’s meeting at 2am.
The good stuff:
- 5-HTP helps your brain make serotonin, which converts to melatonin
- SAM-e tackles the mood side of sleep problems
- Vitamin B6 makes everything work better together
The not-so-good:
- Don’t take this with antidepressants (seriously)
- Results take time – it’s not an immediate lights-out solution
- Might upset your stomach
Nested Naturals Luna Kids Sleep Gummies

This wins the Best for Children’s Sleep Support award. It’s the peace treaty in the bedtime battle.
Because kids need sleep too (and parents REALLY need kids to sleep).
These berry-flavored gummies combine gentle natural ingredients with a kid-appropriate dose of melatonin.
The good stuff:
- Kid-friendly taste and format
- Natural ingredients like valerian root and chamomile
- Free from common allergens and artificial junk
The not-so-good:
- Contains melatonin, so check with your pediatrician first
- Gentle effect might not help serious sleep issues
- Every kid reacts differently
The Bottom Line
There’s no one-size-fits-all sleep supplement.
If you want multi-purpose support, try Jacked Factory’s Lean PM.
If muscle tension keeps you up, go with Magnesium Glycinate.
If your mind races all night, DR. EMIL’s 5-HTP Plus might help.
And if your kids are bouncing off the walls at bedtime, Nested Naturals has you covered.
Remember, supplements aren’t magic pills. They work best alongside good sleep habits like consistent bedtimes, dark rooms, and putting your damn phone down.
Now if you’ll excuse me, I need to catch up on some sleep.